In the US, it is required to have a physician to support you in order to have this test.
The physician will provide ICD-10 codes for potential insurance reimbursement as well as provide result analysis in order to diagnose and create a treatment plan to get you better.
US patients require a supporting physician in order to get this test. We cannot send you a test until you have a doctor who is willing to support you by reviewing your results and creating a treatment plan post result review.
If needed, your physician can schedule a consultation with our infectious disease doctor on staff.
For most accurate results, we test from the closest source of infection(s), where you feel your symptoms. For example, if you have an upset stomach or diarrhea, we would have you do a fecal kit, or for urinary tract infections, we would suggest a urine kit, etc.
US patients require a supporting physician in order to receive the test. Typically, your physician can identify which test kit you will need.
Our cost structure is very simple and provided below;
– $1,000 for 1 kit + $75 for shipping ($200 international)
– $900/ sample for 2 kits + $75 for shipping ($200 international)
– $800/ sample for 3 or more kits + $75 for shipping ($200 international)
On a case by case basis, you may qualify for a payment plan. Please contact firstname.lastname@example.org to see if you qualify (we cannot provide payment plans for international patients, at this time).
Please remember that US patients must have a physician agree to support you in this process before proceeding forward in order to ensure their is a clinician who can provide treatment upon test completion.
Aperiomics is the only company of its kind and scope in the world. It is revolutionizing the way that medical professionals around the world detect and diagnose infections. Supported by the National Science Foundation, Aperiomics identifies every known bacteria, virus, fungus, and parasite through deep shotgun metagenomic sequencing. We help doctors and their patients identify the causes of infections that other tests cannot identify, thus streamlining the path to a positive clinical outcome. Many patients that we have helped were sick for years with no understanding of why. Patients and their physicians often contact Aperiomics after hearing about our life-changing success stories. The complete genetic fingerprint of a sample is created and compared to Aperiomics’ Xplore- PATHO database – a comprehensive database of over 37,000 microorganisms, including the world’s largest collection of known pathogens. Aperiomics was named Life Science’s Innovator of the Year in 2016 and International Start Up of the Year in 2018.
Aperiomics tests for all known bacteria, virus, parasites and fungi based on the sequenced genomes from thousands of scientists around the world. This includes microbes that can cause intestinal issues, urinary tract infections, Lyme disease and many other issues.
We at Aperiomics define parasites as the currently sequenced parasitic worm, amoeba, and archaea genomes. Outside of worms this does not include multicellular things like mites or insects. Mites and multicellular organisms are typically glaringly obvious through a simple microscope and do not require the cutting edge DNA sequencing Aperiomics provides to diagnose.
Aperiomics will want to talk to clinicians for the first time account setups. This is a simple process and we will have someone to help them along the way. An Aperiomics representative will call to notify the clinician’s office when the report is done, that way, you and your physician can sit down with the results and a treatment plan can be created.
Only US patients require a supporting physician.
No, patients or general customers do not need to be sick to be tested. In some cases it may be desired to know one’s normal microbial population. Aperiomics can perform a complete metagenomic microbiome assessment from any clinical sample.
Many patient’s have found it beneficial to know what their healthy body’s microbial state looks like to serve as a baseline for comparison in the event they do become ill in the future.
Chronic Lymes is different from Lymes in that it is thought to be an infectious after effect. Little is known about the most effective treatments or if it’s actually an active lingering infection. Some of our preliminary findings seem to support that the cause is not an active infection caused by known tick bourne vectors although it could be caused by pathogens.
We will not contact doctors until patients submit their sample to us for testing. If patients would like us to contact their doctor before ordering a collection kit, just let us know and we will reach out to them.
Aperiomics typically requires a clinician be involved in the collection and ordering of our testing. This allows for the proper documentation for potential insurance reimbursement, as well as allowing for proper interpretation of results for the patient.
International patients do not need a supporting physician to order the test.
Yes! All known forms of Lyme and tick-bourne diseases are in the Aperiomics Microbial Database. Since Lyme Disease is very cryptic and likes to hide itself in various parts of the body, we recommend collection of blood, swab, urine and fecal samples to best chance of capturing the pathogen in the collection kits.
In some cases, if there is not a clear, single site of infection (or symptom), we will request that multiple samples be collected and tested. In this case, we will request multiple sample to ensure the best possible results.
When collected as instructed, samples are rendered non-infectious and stable at ambient temperatures for up to 30 days. The supplied shipping materials will return the sample next-day, and thus no special concerns are needed when shipping samples back to Aperiomics.
Your physician (for US patients only) and you will receive your results within 10-14 days after sample is returned to Aperiomics.
For us to get the best possible sample, it is typically recommended that all anti-infective treatments (antifungals, antiparasitics, antibiotics) be stopped 3 days prior to sample collection. This should be discussed with a healthcare provider.
Probiotics should be stopped 14 days prior. All anti-infective treatments and probiotics should be listed on the requisition form, so our infectious disease doctor is aware of this when interpreting your results during the post- results physician consultation.
No. Our specialized collection kits contain a solution that renders samples non-infectious and keeps the genetic material that we need intact for up to 30 days at room temperature. Combined with our supplied packing materials, it also makes it safe for shipping… so no need to worry.
Physicians should be able to tell patients which kit or kits they’ll need to help identify the pathogens causing your illness. While a single kit may be needed, in some instances patients may require additional kits (blood, swab, urine, fecal, tissue or semen) to capture the pathogens at the suspected source of the infection.
For most accurate results, we test from the closest source of infection(s), where you feel your symptoms. For example, if you have an upset stomach or diarrhea, we would have you do a fecal kit, or for urinary tract infections, we would suggest a urine kit, etc. If there are NO CLEAR SIGNS OF SYMPTOMS, we suggest a blood plasma kit.
Testing typically takes 10- 14 days.
Once your results are returned to your physician (physician required by US patients only), you can set up a consultation with our infectious disease doctor on staff. They will help your physician understand and interpret the results if needed.
Results are sent to healthcare providers securely and directly. For international patients, results are sent to you or your physician on file (if applicable).
If needed, one can schedule a consultation with our infectious disease doctor on staff to interpret and understand patient results.
A healthcare provider, analyzing our results along with the patient’s clinical history, will help patient’s understand the results of their testing.
We provide one-on-one support for healthcare providers to understand our reports and help your physician gain the context needed for them to diagnose and create a treatment plan.
Aperiomics is now providing insurance billing on a case-by-case basis. To determine if a patient’s insurance coverage qualifies for us to bill our services, we will need to do a verification of benefits prior to any testing. Patients will need to send their name, date of birth, contact information, and copies of the front and back of the patient’s insurance card to email@example.com. After the verification of benefits is complete, we will contact the patient with the details of your coverage, including any out of pocket payment required before we start testing. Please allow 24-48 hours for insurance to respond to us with your coverage details. In some cases, patients will only be required to pay a $200/sample co-insurance plus shipping/handling charges. Please contact us for details.
Payment is typically done up front as is standard in most testing companies. Once you have a supporting physician agree to provide treatment and sign the requisition form (physician required for US patients only), we will send you a secure invoice through email. We will ship you the kit after we receive confirmation of your payment.
Most labs test for just one or a handful of pathogens at a time. Others are only focuse on one aspect like bacteria. Aperiomics tests for ALL known pathogens at once! This is the most comprehensive testing available on the market and one of the best options for identifying chronic or cryptic infections.
Culture is a 100+ year old technology that is limited to identifying only what will grow in culture. Given that many microorganisms will not grow in culture, this technology is dramatically limited in the number of microorganisms that can be identified. Culture creates bias because just one bacterial cell can grow and render a sample positive for that bacteria, irrespective of if that bacteria is causing an active infection. Additionally, culture does not allow for consistent, objective identification of microorganisms to the species level.
Not all NGS techniques are the same though, there are multiple different forms. Some, used by our competitors only look at bacteria and have difficulty looking at the species and strain level. The type of NGS we use, called shotgun metagenomic sequencing, is one of the most powerful among NGS techniques able to do it all.
Shotgun metagenomics is more specific than culture can be because it identifies the identity of microorganisms according to the genetic sequence and not simply appearance of growth in culture.
PCR is a technology that makes many copies of a small portion of a microorganism’s genetic information. It can be inexpensive and sensitive, but is extremely limited in how many microorganisms can be identified in a single test – typically less than a dozen in one test. Further, because PCR creates many copies of small genetic pieces, it is heavily biased and cannot be used to assess abundance of microbial populations.
In contrast, NGS (shotgun metagenomic sequencing) creates a genetic fingerprint of everything in the sample. It is a much more comprehensive approach, capable of identifying tens of thousands of microorganisms in one sample, only limited by the availability of sequence data. Aperiomics’ approach to NGS reduces as much bias as possible and allows abundance of microbial populations to be assessed.
16S NGS is similar to PCR in that it creates many copies of specific genetic information. These copies are then compared to a database to identify the bacteria present in a given sample. 16S sequencing is good at identifying thousands of bacteria to the genus level, but is unable to identify virus, fungi, or parasites. Deep shotgun metagenomics sequencing, on the other hand, is able to identify tens of thousands of microorganisms and differentiate species of bacteria, virus, parasites, and fungi.
Items that are in the pipeline or in development now include drug resistance identification, the ability to identify true unknowns, disease prediction and biosurveillance.
Taking probiotics while submitting a stool sample will severely hamper your results. We recommend stopping all probiotics at least two weeks prior to submitting a stool sample to us.